The AP1G1 Monoclonal Antibody (CAB20454) is a powerful tool for researchers studying AP1G1, a key protein involved in intracellular transport and vesicle formation. This antibody, generated in mice, has high specificity and sensitivity for AP1G1 in human samples, making it ideal for use in a variety of research applications, including Western blotting and immunofluorescence.AP1G1 is a crucial component of the AP-1 protein complex, which plays a vital role in the sorting and trafficking of proteins within cells. Dysregulation of AP1G1 function has been implicated in various diseases, including neurological disorders and metabolic syndromes.
By targeting AP1G1 with this antibody, researchers can gain insights into the intricate mechanisms of intracellular transport and potentially identify new therapeutic targets for these conditions.With its proven reliability and specificity, the AP1G1 Monoclonal Antibody (CAB20454) is a valuable tool for scientists looking to advance their understanding of cellular processes and explore new avenues for therapeutic intervention in disease.
Product Name:
AP1G1 Rabbit Polyclonal Antibody
SKU:
CAB20454
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human AP1G1 (NP_001025178).
clathrin-coated pit, clathrin-coated vesicle, cytoplasm, cytosol, early endosome, Golgi apparatus, perinuclear region of cytoplasm, recycling endosome
Calculated MW:
91kDa
Observed MW:
91kDa
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
164
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AP1G1 Rabbit pAb (CAB20454) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
