The AP1G1 Polyclonal Antibody (CAB19269) is a valuable tool for researchers studying AP1G1, a key adaptor protein involved in intracellular trafficking and vesicle formation. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the AP1G1 protein, researchers can easily detect and analyze its expression in various cell types, making it an ideal choice for studies in cell biology and molecular biology.AP1G1 plays a crucial role in regulating the sorting and trafficking of proteins within cells, making it essential for maintaining cellular function and organization. Dysregulation of AP1G1 has been linked to various diseases, including neurodegenerative disorders and certain types of cancer.
By studying the function of AP1G1, researchers can gain valuable insights into these disease mechanisms and potentially identify new therapeutic targets for treatment.Investigating the role of AP1G1 with the AP1G1 Polyclonal Antibody (CAB19269) can provide crucial information for understanding intracellular trafficking pathways and their implications in disease progression. With its high specificity and reliability in Western blotting, this antibody is a powerful tool for advancing research in the fields of cell biology, molecular biology, and disease pathology.
Product Name:
AP1G1 Rabbit Monoclonal Antibody
SKU:
CAB19269
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 723-822 of human AP1G1 (O43747).
clathrin-coated pit, clathrin-coated vesicle, cytoplasm, cytosol, early endosome, Golgi apparatus, perinuclear region of cytoplasm, recycling endosome
Calculated MW:
91kDa
Observed MW:
100kDa
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
164
Clone Number:
ARC2440
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using AP1G1 Rabbit mAb (CAB19269) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
