ANPRB/NRP2 Rabbit Monoclonal Antibody (CAB19255)
- SKU:
- CAB19255
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NPR2
- AMDM
- ANPRB
- ANPb
- ECDM
- GUC2B
- GUCY2B
- NPRB
- NPRBi
- SNSK
- natriuretic peptide receptor 2
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ANPRB/NRP2 Rabbit Monoclonal Antibody |
SKU: | CAB19255 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ANPRB/NRP2 (P20594). |
Sequence: | NLLL RMEQ YANN LEKL VEER TQAY LEEK RKAE ALLY QILP HSVA EQLK RGET VQAE AFDS VTIY FSDI VGFT ALSA ESTP MQVV TLLN DLYT CFDA IIDN F |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GCB; AMD1; AMDM; ANPb; ECDM; GC-B; NPRB; SNSK; ANPRB; GUC2B; NPRBi; GUCY2B; ANPRB/NRP2 |
Positive Sample: | Mouse lung,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein |
Calculated MW: | 117kDa |
Observed MW: | 130kDa |
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.
Purification Method: | Affinity purification |
Gene ID: | 4882 |
Clone Number: | ARC2421 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |