The Anti-Alpha SNAP Antibody (CAB19227) is a polyclonal antibody designed for research involving Alpha SNAP, a key protein involved in intracellular membrane fusion and trafficking processes. The antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in various applications, including Western blot and immunofluorescence.Alpha SNAP plays a crucial role in the regulation of vesicle fusion and neurotransmitter release, making it a significant target for studies in neuroscience and cell biology. By binding to Alpha SNAP, this antibody enables the detection and analysis of the protein in different cell types, providing valuable insights into its function and regulation.
Furthermore, Alpha SNAP has been implicated in various neurological disorders and synaptic dysfunctions, making it a promising target for research into neurodegenerative diseases and neurodevelopmental disorders. Understanding the role of Alpha SNAP in these conditions could lead to the development of novel therapeutic strategies and interventions.Overall, the Anti-Alpha SNAP Antibody (CAB19227) offers researchers a highly specific and reliable tool for investigating the function and implications of Alpha SNAP in both normal physiological processes and disease states.
Product Name:
Alpha SNAP Rabbit Monoclonal Antibody
SKU:
CAB19227
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-295 of human Alpha SNAP (P54920).
This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8775
Clone Number:
ARC2382
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Alpha SNAP antibody (CAB19227) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
