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alpha 1 Spectrin Rabbit Monoclonal Antibody (CAB9597)

SKU:
CAB9597
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:alpha 1 Spectrin Rabbit Monoclonal Antibody
SKU:CAB9597
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 2300-2400 of human alpha 1 Spectrin (P02549).
Sequence:LRGL NYYL PMVE EDEH EPKF EKFL DAVD PGRK GYVS LEDY TAFL IDKE SENI KSSD EIEN AFQA LAEG KSYI TKED MKQA LTPE QVSF CATH MQQY MDPR G
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:EL2; HPP; HS3; SPH3; SPTA; alpha 1 Spectrin
Positive Sample:K-562,Mouse lung,Rat heart
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, cell cortex, cytoskeleton.
Calculated MW:280kDa
Observed MW:280kDa

This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3.

Purification Method:Affinity purification
Gene ID:6708
Clone Number:ARC1650
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using alpha 1 Spectrin Rabbit mAb (CAB9597) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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