ALDH7A1 Monoclonal Antibody (CAB20888)
- SKU:
- CAB20888
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Plant
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Product Name: | ALDH7A1 Monoclonal Antibody |
| SKU: | CAB20888 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ALDH7A1 (P49419). |
| Sequence: | MWRL PRAL CVHA AKTS KLSG PWSR PAAF MSTL LINQ PQYA WLKE LGLR EENE GVYN GSWG GRGE VITT YCPA NNEP IARV RQAS VADY EETV KKAR EAWK |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:100 - 1:500 |
| Synonyms: | EPD; PDE; ATQ1; ALDH7A1 |
| Positive Sample: | HeLa,Hep G2,SH-SY5Y,Mouse liver,Mouse kidney |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm, Cytosol, Mitochondrion, Nucleus. |
| Calculated MW: | 58kDa |
| Observed MW: | 58kDa |
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.
| Purification Method: | Affinity purification |
| Gene ID: | 501 |
| Clone Number: | ARC2837 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of extracts of various cell lines, using ALDH7A1 antibody (CAB20888) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s. |
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