AhR Rabbit Monoclonal Antibody (CAB4000)
- SKU:
- CAB4000
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- bHLHe76
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AhR Rabbit Monoclonal Antibody |
SKU: | CAB4000 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 619-848 of human AHR (NP_001612.1). |
Sequence: | LEQQ QQHH QKQV VVEP QQQL CQKM KHMQ VNGM FENW NSNQ FVPF NCPQ QDPQ QYNV FTDL HGIS QEFP YKSE MDSM PYTQ NFIS CNQP VLPQ HSKC TELD YPMG SFEP SPYP TTSS LEDF VTCL QLPE NQKH GLNP QSAI ITPQ TCYA GAVS MYQC QPEP QHTH VGQM QYNP VLPG QQAF LNKF QNGV LNET YPAE LNNI NNTQ TTTH LQPL HHPS EARP FPDL TSSG FL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | RP85; bHLHe76; AHR |
Positive Sample: | HepG2,PC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, cytosolic aryl hydrocarbon receptor complex, nuclear aryl hydrocarbon receptor complex, nucleoplasm, nucleus |
Calculated MW: | 96kDa |
Observed MW: | 100kDa |
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.
Purification Method: | Affinity purification |
Gene ID: | 196 |
Clone Number: | ARC53212 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |