The Anti-ADRA1A Antibody (CAB9410) is a high-quality research tool for studying the ADRA1A protein, a member of the adrenergic receptor family involved in regulating neurotransmission and blood vessel tone. This polyclonal antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.ADRA1A is known to play a key role in the sympathetic nervous system, making it a target of interest in various research fields such as neuroscience, cardiovascular biology, and pharmacology. By binding specifically to the ADRA1A protein, this antibody allows for accurate detection and analysis in different cell types, providing researchers with valuable insights into its function and potential therapeutic implications.
With its ability to target ADRA1A, the Anti-ADRA1A Antibody (CAB9410) is an essential tool for investigating the role of this protein in physiological and pathological conditions, including hypertension, heart failure, and neurological disorders. By elucidating the mechanisms underlying ADRA1A signaling, researchers can pave the way for the development of novel therapies targeting this receptor for various disease states.
Product Name:
ADRA1A Monoclonal Antibody
SKU:
CAB9410
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human ADRA1A (P35348).
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Purification Method:
Affinity purification
Gene ID:
148
Clone Number:
ARC2740
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using (CAB9410) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
