The Anti-ADGRE2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0253) is a specialized antibody designed for research involving ADGRE2, also known as EGF-like module-containing mucin-like hormone receptor-like 2 (EMR2). ADGRE2 is a cell surface molecule involved in immune regulation, particularly in mediating immune responses.This antibody, developed in rabbits, exhibits high reactivity with human samples and has been thoroughly validated for Western blot applications. By binding specifically to the ADGRE2 protein, it enables the detection and analysis of ADGRE2 in a variety of cell types, making it well-suited for investigations in immunology and cancer research.ADGRE2 is known for its role as an adhesion G-protein-coupled receptor that is involved in mediating cell-cell interactions and immune responses.
Its functions in immune regulation make it a promising target for research into immune-related diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Studying the activity of ADGRE2 is essential for advancing the development of therapies that target or modulate immune responses in these diseases.Overall, the Anti-ADGRE2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0253) is a valuable tool for researchers studying the role of ADGRE2 in immune regulation and its implications for various disease states.
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
