The Anti-Adenylate Kinase 4 Antibody (CAB2383) is a valuable tool for researchers investigating adenylate kinase 4, a key enzyme involved in cellular energy metabolism. This polyclonal antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding specifically to adenylate kinase 4, this antibody allows for accurate detection and analysis of this important protein in a variety of cell types.Adenylate kinase 4 is known to play a crucial role in regulating energy balance within the cell, making it a potential target for research into metabolic disorders, cancer, and other diseases linked to dysregulated cellular metabolism.
By understanding the function and regulation of adenylate kinase 4, researchers may uncover new insights into the mechanisms driving these conditions and potentially identify novel therapeutic strategies for treatment.Overall, the Anti-Adenylate Kinase 4 Antibody (CAB2383) offers researchers a powerful tool for exploring the role of adenylate kinase 4 in health and disease, with potential implications for the development of novel therapies in the future.
Product Name:
Adenylate kinase 4 Rabbit Monoclonal Antibody
SKU:
CAB2383
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Adenylate kinase 4 (P27144).
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
Purification Method:
Affinity purification
Gene ID:
205
Clone Number:
ARC2572
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Adenylate kinase 4 Rabbit mAb (CAB2383) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.