ACVRL1 Rabbit Monoclonal Antibody (CAB9755)
- SKU:
- CAB9755
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ACVRLK1
- ALK-1
- ALK1
- HHT
- HHT2
- ORW2
- SKR3
- TSR-I
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | ACVRL1 Rabbit Monoclonal Antibody |
SKU: | CAB9755 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 404-503 of human ACVRL1 (P37023). |
Sequence: | VLWE IARR TIVN GIVE DYRP PFYD VVPN DPSF EDMK KVVC VDQQ TPTI PNRL AADP VLSG LAQM MREC WYPN PSAR LTAL RIKK TLQK ISNS PEKP KVIQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; ACVRL1 |
Positive Sample: | 293T,Mouse spleen,Mouse kidney,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 56kDa |
Observed MW: | 60kDa |
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Purification Method: | Affinity purification |
Gene ID: | 94 |
Clone Number: | ARC1735 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |