Acetyl-Histone H3-K23 Rabbit Monoclonal Antibody (CAB2771)
- SKU:
- CAB2771
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- WB
- IHC
- IF
- IP
- ChIP
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Acetyl-Histone H3-K23 Rabbit Monoclonal Antibody |
SKU: | CAB2771 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Other (Wide Range Predicted) |
Immunogen: | A synthetic acetylated peptide around K27 of human Histone H3 (P68431). |
Sequence: | MART KQTA RKST GGKA PRKQ LATK AARK SAPA TGGV KKPH RYRP GTVA LREI RRYQ KSTE LLIR KLPF QRLV REIA QDFK TDLR FQSS AVMA LQEA CEAY |
Tested Applications: | WB IHC-P IF/ICC IP ChIP ELISA DB |
Recommended Dilution: | DB,1:500 - 1:2000 WB,1:10000 - 1:120000 IHC-P,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsIF/ICC,1:50 - 1:200 ChIP,2μg antibody for 5μg-10μg of Chromatin |
Positive Sample: | HeLa TSA, NIH/3T3 TSA ,C6 TSA |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus |
Calculated MW: | 15kDa |
Observed MW: | 17kDa |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Purification Method: | Affinity purification |
Gene ID: | 8290/8350 |
Clone Number: | ARC53670 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |