The Anti-Acetyl Histone H1.4 (K26) Antibody (CAB17893) is a valuable tool for researchers studying epigenetics and chromatin modifications. This antibody, raised against acetylated histone H1.4 at lysine 26, is highly specific and sensitive for detecting this modification in various samples.Histone acetylation at specific residues, such as lysine 26 on histone H1.4, plays a crucial role in regulating gene expression and chromatin structure. By targeting this modification, researchers can investigate the impact of acetylation on gene regulation, cell signaling, and disease development.The CAB17893 antibody is validated for use in Western blot applications, allowing for the detection and analysis of acetylated histone H1.
4 in different cell types and tissues. Its high reactivity with human samples makes it an ideal tool for research in the fields of epigenetics, cancer biology, and developmental biology.Overall, the Anti-Acetyl Histone H1.4 (K26) Antibody (CAB17893) provides researchers with a reliable tool for investigating the role of histone acetylation in gene regulation and cellular processes, ultimately advancing our understanding of epigenetic mechanisms in health and disease.
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Purification Method:
Affinity purification
Gene ID:
3008
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded rat ovary using Acetyl-Histone H1.4-K26 Rabbit pAb (CAB17893) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
