The Anti-ACAT2 Antibody (CAB1399) is a valuable tool for researchers studying ACAT2, an enzyme involved in cholesterol metabolism and lipid storage. This polyclonal antibody, produced in rabbits, is highly specific to human ACAT2 and is ideal for use in Western blot applications. By binding to the ACAT2 protein, this antibody enables precise detection and analysis in various cell types, making it essential for research in lipid metabolism, atherosclerosis, and other related fields.ACAT2 is a key player in cholesterol esterification, the process by which cholesterol is stored in cells. Dysregulation of ACAT2 activity has been linked to conditions such as atherosclerosis and other cardiovascular diseases.
Therefore, understanding the function and regulation of ACAT2 is crucial for developing targeted therapies to combat these health issues.By using the Anti-ACAT2 Antibody in their research, scientists can gain valuable insights into the role of ACAT2 in lipid metabolism and its implications for human health. This antibody is a reliable tool for investigating ACAT2 function and may lead to new advancements in the treatment and prevention of cholesterol-related disorders.
Product Name:
ACAT2 Rabbit Monoclonal Antibody
SKU:
CAB1399
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human ACAT2 (Q9BWD1).
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
39
Clone Number:
ARC2560
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ACAT2 antibody (CAB1399) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
