The ABL2 Polyclonal Antibody (CAB19628) is a valuable tool for researchers studying the ABL2 protein, a key player in cell signaling pathways and cancer development. This antibody, produced in rabbits, has been rigorously validated for Western blot applications and shows high reactivity with human samples.ABL2, also known as Abelson tyrosine-protein kinase 2, is involved in various cellular processes such as cell growth, differentiation, and migration. Dysregulation of ABL2 has been linked to cancer progression, making it a promising therapeutic target for cancer treatment.
By using the ABL2 Polyclonal Antibody, researchers can detect and analyze the ABL2 protein in different cell types, aiding in the understanding of its role in cancer development and progression. This antibody is an essential tool for studies in oncology and cell signaling pathways, providing valuable insights into potential targeted therapies for cancer treatment.
Product Name:
ABL2 Rabbit Monoclonal Antibody
SKU:
CAB19628
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human ABL2 (P42684).
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
27
Clone Number:
ARC2200
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ABL2 Rabbit mAb (CAB19628) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
