The ABCA8A Monoclonal Antibody (CAB20496) is a powerful tool for researchers studying ABCA8A, a member of the ATP-binding cassette (ABC) transporter family known to play a crucial role in lipid trafficking and metabolism. This antibody, produced through a unique monoclonal antibody development process, specifically targets the ABCA8A protein, allowing for accurate detection and analysis in a variety of experimental settings.ABCA8A is widely expressed in various tissues, with particularly high levels in liver and adipose tissue. Its involvement in lipid transport and metabolism suggests a potential role in metabolic disorders such as obesity and diabetes, making it a promising target for further investigation.
The ABCA8A Monoclonal Antibody is ideal for probing ABCA8A levels and localization in different cell types, aiding in the understanding of its function and potential therapeutic implications in metabolic diseases.With its high specificity and sensitivity, the ABCA8A Monoclonal Antibody is a valuable tool for researchers studying lipid metabolism, metabolic diseases, and related pathways. Its reliable performance in techniques such as Western blot and immunofluorescence makes it a versatile asset in the fields of molecular biology, biochemistry, and pharmacology. Unlock the potential of ABCA8A research with the ABCA8A Monoclonal Antibody (CAB20496).
Product Name:
ABCA8A Rabbit Polyclonal Antibody
SKU:
CAB20496
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 690-828 of mouse ABCA8A (NP_694785.3).
Predicted to enable ABC-type xenobiotic transporter activity and lipid transporter activity. Predicted to be involved in several processes, including cholesterol efflux; positive regulation of cholesterol efflux; and sphingomyelin biosynthetic process. Predicted to be located in endoplasmic reticulum and plasma membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in telencephalon. Orthologous to human ABCA8 (ATP binding cassette subfamily A member 8).
Purification Method:
Affinity purification
Gene ID:
217258
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using ABCA8A Rabbit pAb (CAB20496) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
