The ABCA8 Monoclonal Antibody (CAB20553) is a powerful tool for researchers studying ABCA8, a member of the ATP-binding cassette (ABC) transporter family implicated in lipid transport and metabolism. This antibody, developed using cutting-edge technology, is highly specific to human ABCA8 and has been rigorously tested for use in various applications including immunofluorescence and flow cytometry.ABCA8 is known to play a key role in cellular lipid homeostasis and has been linked to various diseases such as atherosclerosis and metabolic disorders. By targeting ABCA8, researchers can gain valuable insights into the mechanisms underlying lipid-related diseases and potentially identify novel therapeutic targets for intervention.
With its high specificity and reliability, the ABCA8 Monoclonal Antibody (CAB20553) is an essential tool for researchers working in the fields of lipid biology, cardiovascular research, and metabolic diseases. By enabling accurate detection and analysis of ABCA8 protein expression, this antibody facilitates groundbreaking discoveries that have the potential to revolutionize the treatment of lipid-related disorders.
Product Name:
ABCA8 Rabbit Polyclonal Antibody
SKU:
CAB20553
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 425-495 of human ABCA8 (NP_009099.1).
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10351
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ABCA8 antibody (CAB20553) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
