The Anti-A-Raf Antibody (CAB8687) is a valuable tool for researchers studying the A-Raf protein, a member of the Raf kinase family involved in cellular signal transduction pathways. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the A-Raf protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in cellular signaling, cancer biology, and drug development.A-Raf is known for its role in regulating cell growth, differentiation, and survival, and its dysregulation has been implicated in various cancers and other diseases.
By studying the function of A-Raf using this antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets. Understanding the role of A-Raf in cellular signaling pathways is essential for developing novel treatments and improving patient outcomes in cancer and other related conditions.
Product Name:
A-RAF Rabbit Monoclonal Antibody
SKU:
CAB8687
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 166-290 of human A-RAF (P10398).
Enables protein serine/threonine kinase activity. Involved in negative regulation of apoptotic process; regulation of TOR signaling; and regulation of cellular protein metabolic process. Predicted to be active in cytosol and mitochondrion. Biomarker of high grade glioma.
Purification Method:
Affinity purification
Gene ID:
369
Clone Number:
ARC1782
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using A-RAF Rabbit mAb (CAB8687) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
