The Anti-5-methylcytidine (5-mC) Antibody (CAB18870) is a highly specific antibody designed for research involving the detection of 5-mC, a key epigenetic modification involved in gene regulation and chromatin structure. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including immunohistochemistry and immunofluorescence.5-mC is a methylated form of cytidine found in DNA and RNA, playing a crucial role in gene expression regulation, cellular differentiation, and development. Dysregulation of 5-mC has been implicated in various diseases, including cancer, neurodevelopmental disorders, and metabolic disorders.
Understanding the distribution and levels of 5-mC in cells and tissues is essential for unraveling its role in disease development and progression.Researchers studying epigenetics, DNA methylation, and gene regulation will find the Anti-5-methylcytidine (5-mC) Antibody (CAB18870) to be a valuable tool for investigating the dynamic changes in 5-mC levels and distribution under different biological conditions. Its specificity and sensitivity make it an ideal choice for studies aimed at understanding the impact of epigenetic modifications on cellular function and disease processes.
Product Name:
5-methylcytidine/m5C Rabbit pAb
Product Code:
CAB18870
Size:
50uL, 100uL
Applications:
DB
Reactivity:
Human, Mouse, Rat, Other (Wide Range)
Host Species:
Rabbit
Immunogen:
Chemical compounds corresponding to 5-methylcytidine
Applications:
DB
Recommended Dilutions:
DB 1:500 - 1:2000
Reactivity:
Human, Mouse, Rat, Other (Wide Range)
Immunogen:
Chemical compounds corresponding to 5-methylcytidine
Purification Method:
Affinity purification
Storage:
Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.