2'-O-Methylguanosine(Gm) Polyclonal Antibody (CAB20697)
- SKU:
- CAB20697
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Product Name: | 2'-O-Methylguanosine(Gm) Polyclonal Antibody |
| SKU: | CAB20697 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Species independent |
| Immunogen: | Gm |
| Sequence: | Gm c onju gate d to KLH |
| Tested Applications: | ELISA DB |
| Recommended Dilution: | DB,1:500 - 1:2000 |
| Conjugate: | Unconjugated |
| Observed MW: | Refer to figures |
RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2'-O-methyladenosine (Am), 2'-O-methylguanosine (Gm),2'-O-methylcytidine (Cm),2'-O-methyluridine (Um),N 6-methyladenosine (m6A), N 1-methylguanosine (m1G),5-methylcytidine (m5C),and 5-methyluridine (m5U) are representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA.
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
 | The 2'-O-methylguanosine(Gm) Rabbit pAb(CAB20697) are tested in Dot Blot against 2'-O-methylguanosine(Gm) and unmodified guanosine. Gm-3：5'Biotin-GCATAATGACTACT(Gm)3' Gm-4：5'Biotin-GCATAATGACTACTG3' |
Related Products
2'-O-methylcytidine/ Cm Rabbit Polyclonal Antibody (CAB20306)
2'-O-methyluridine(Um) Rabbit Polyclonal Antibody (CAB20305)
Human GM-CSF Polyclonal Antibody (CAB22109)
Lipocalin-2/NGAL Polyclonal Antibody