The Anti-2'-O-Methylguanosine (GM) Antibody (CAB20696) is a valuable tool for research involving the detection and analysis of 2'-O-Methylguanosine, a modified nucleoside commonly found in RNA. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting.2'-O-Methylguanosine is known to play important roles in RNA processing and function, making it a key molecule of interest in the fields of molecular biology and biochemistry. This antibody specifically binds to 2'-O-Methylguanosine, allowing for accurate detection and analysis of this modified nucleoside in various biological samples.
Researchers in the fields of RNA biology, epigenetics, and nucleic acid research will find the Anti-2'-O-Methylguanosine (GM) Antibody (CAB20696) to be a valuable asset in their studies. By utilizing this antibody, scientists can gain insights into the functions and regulations of 2'-O-Methylguanosine in RNA molecules, further advancing our understanding of gene expression and cellular processes.
RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2'-O-methyladenosine (Am), 2'-O-methylguanosine (Gm),2'-O-methylcytidine (Cm),2'-O-methyluridine (Um),N 6-methyladenosine (m6A), N 1-methylguanosine (m1G),5-methylcytidine (m5C),and 5-methyluridine (m5U) are representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA.
Purification Method:
Affinity purification
Gene ID:
CAS: 2140-71-8
Clone Number:
ARC50772
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
The 2'-O-methylguanosine(Gm) Rabbit mAb (CAB20696) are tested in Dot Blot against 2'-O-methylguanosine and unmodified guanosine.2'-O-methylguanosine：Biotin-5'GCATAATGACTACT(Gm)3'unmodified guanosine：Biotin-5'GCATAATGACTACTG3'
