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2'-O-Methylguanosine(Gm) Monoclonal Antibody (CAB20696)

SKU:
CAB20696
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
€179 - €469
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:2'-O-Methylguanosine(Gm) Monoclonal Antibody
SKU:CAB20696
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Species independent
Immunogen:Gm
Sequence:Gm c onju gate d to KLH
Tested Applications:ELISA DB
Recommended Dilution:DB,1:500 - 1:2000
Synonyms:2'-O-Methylguanosine; Gm; 2'-O-Methylguanosine(Gm)
Conjugate:Unconjugated
Observed MW:Refer to figures

RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2'-O-methyladenosine (Am), 2'-O-methylguanosine (Gm),2'-O-methylcytidine (Cm),2'-O-methyluridine (Um),N 6-methyladenosine (m6A), N 1-methylguanosine (m1G),5-methylcytidine (m5C),and 5-methyluridine (m5U) are representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA.

Purification Method:Affinity purification
Gene ID:CAS: 2140-71-8
Clone Number:ARC50772
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageThe 2'-O-methylguanosine(Gm) Rabbit mAb (CAB20696) are tested in Dot Blot against 2'-O-methylguanosine and unmodified guanosine.2'-O-methylguanosine：Biotin-5'GCATAATGACTACT(Gm)3'unmodified guanosine：Biotin-5'GCATAATGACTACTG3'

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