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Anthrax PA Monoclonal Antibody (CPAB0712)

SKU:
CPAB0712
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Virus
Applications:
WB
$2,336
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:Anthrax PA Antibody
Product Sku:CPAB0712
Size:200μl
Host Species:
Immunogen:Anthrax PA Antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 24-254 of the Anthrax PA protein (~83 kD)Anthrax PA Antibody is cleaved from the 83 kDa form to the 63 kDa form at amino acids 164-167Thus the Anthrax PA antibody (made against amino acids 25-25) should recognize both the 83 kDa and 63 kDa PA forms, but not the 2 kDa cleavage fragment.
Clone:
Reactivity:Viral
Applications:Western Blot
Purification Method:
Isotype:
Background:Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family(2).
Synonyms:
Storage Buffer:

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