Anthrax LF Monoclonal Antibody (CPAB0711)
- SKU:
- CPAB0711
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Virus
- Applications:
- WB
Frequently bought together:
Description
system_update_alt Datasheet
| Product Name: | Anthrax LF Antibody |
| Product Sku: | CPAB0711 |
| Size: | 200μl |
| Host Species: | |
| Immunogen: | The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 47-65 of the Anthrax LF protein (~9 kD). |
| Clone: | |
| Reactivity: | Viral |
| Applications: | Western Blot |
| Purification Method: | |
| Isotype: | |
| Background: | Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family(2). |
| Synonyms: | |
| Storage Buffer: |
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