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GenieFluor 647 Anti-Mouse CD3 Antibody [17A2] (AGEL0104)

SKU:
AGEL0104
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
17A2
Conjugation:
AF 647
Applications:
FC
€109 - €249
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody (Alexa Fluor 647 Conjugated, 17A2) (AGEL0104) is a cutting-edge tool for research involving CD3, a crucial T cell receptor complex involved in immune responses. This monoclonal antibody, derived from mouse hybridoma cells, demonstrates high specificity and sensitivity in detecting CD3 protein expression in various cellular contexts.CD3 is pivotal for T cell activation and function, playing a central role in adaptive immunity. By targeting CD3, researchers can gain insights into T cell signaling, activation, and responses to antigens, making this antibody an invaluable asset for immunology studies, vaccine development, and understanding immune-related diseases.

The Alexa Fluor 647 conjugation enhances the antibody's detection capabilities, allowing for precise visualization and quantification of CD3-expressing cells through fluorescence-based techniques such as flow cytometry and immunofluorescence microscopy. The versatility and reliability of this antibody make it an essential tool for investigating T cell biology, immune system dynamics, and therapeutic strategies targeting T cell-mediated immune responses.

Product Title:GenieFluor 647 Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0104
Size:50 Tests, 100 Tests, 200 Tests
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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