The ANP32D Antibody (PAC047302) is a vital tool for researchers studying ANP32D, a protein belonging to the acidic nuclear phosphoprotein 32 family. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is validated for Western blot applications. By binding to ANP32D, researchers can reliably detect and analyze this protein in a variety of cell types, making it a valuable asset for investigations in molecular biology and cancer research.
ANP32D is known for its involvement in various cellular processes, including transcription and apoptosis. Its role in regulating gene expression and cell survival makes it a promising target for studying cancer development and progression. By delving into the functions of ANP32D, researchers can gain insights that may lead to innovative approaches for cancer therapy and treatment strategies.
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO47302 at dilution of 1:100.
Immunofluorescent analysis of Hela cells using PACO47302 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
acid, c leucine-rich nuclear phosphoprotein 32 family member D (Phosphoprotein 32-related protein 2) (Tumorigenic protein pp32r2), ANP32D, PP32R2
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]
