The ANO7 Antibody (PACO02953) offered by Assay Genie is a valuable tool for research studies involving ANO7, a protein linked to various cellular processes. This polyclonal antibody, produced using state-of-the-art techniques, exhibits high specificity and sensitivity in detecting ANO7 in human samples. It has been validated for use in applications such as Western blotting, immunofluorescence, and immunohistochemistry.ANO7, a member of the anoctamin family of proteins, has been implicated in ion channel regulation, lipid scrambling, and membrane fusion events. Its functional significance in cellular physiology and potential involvement in disease pathology make it a compelling target for further investigation.
The ANO7 Antibody can facilitate the visualization and analysis of ANO7 expression and localization in different cell types, aiding researchers in unraveling its biological roles and molecular mechanisms.With its ability to provide critical insights into ANO7 biology and function, this antibody is an essential tool for studies in cell biology, physiology, and disease research. By elucidating the functions of ANO7, researchers can advance our understanding of cellular physiology and potentially discover new therapeutic strategies for conditions influenced by ANO7 dysregulation.
Antibody Name:
ANO7 Antibody
Antibody SKU:
PACO02953
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human NGEP.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ANO7; NGEP; PCANAP5; TMEM16G; Anoctamin-7; Dresden transmembrane protein of the prostate; D-TMPP; IPCA-5; New gene expressed in prostate; Prostate cancer-associated protein 5; Transmembrane protein 16G
UniProt Protein Function:
ANO7: May act as a calcium-activated chloride channel. May play a role in cell-cell interactions. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter, ion channel; Channel, chloride; Calcium-binding; Membrane protein, integral; Transporter; Membrane protein, multi-passChromosomal Location of Human Ortholog: 2q37.3Cellular Component: endoplasmic reticulum; integral to membrane; plasma membrane; intracellular; nucleus; cytosol; cell junctionMolecular Function: phospholipid scramblase activity; intracellular calcium activated chloride channel activityBiological Process: chloride transport; lipid transport; transmembrane transport
UniProt Protein Details:
NCBI Summary:
This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011]
NGEP; DTMPP; IPCA5; D-TMPP; IPCA-5; PCANAP5; TMEM16G; PCANAP5LÂ Â
NCBI Protein Information:
anoctamin-7; transmembrane protein 16G; prostate cancer associated protein 5; Dresden-transmembrane protein of the prostate
UniProt Protein Name:
Anoctamin-7
UniProt Synonym Protein Names:
Dresden transmembrane protein of the prostate; D-TMPP; IPCA-5; New gene expressed in prostate; Prostate cancer-associated protein 5; Transmembrane protein 16G
