The ANO5 Polyclonal Antibody (CAB15218) is a valuable tool for researchers studying ANO5, a calcium-activated chloride channel protein involved in muscle function and membrane repair. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ANO5 protein, this antibody enables the detection and analysis of ANO5 expression in various cell types, making it ideal for investigations in muscle biology and membrane repair mechanisms.ANO5, also known as TMEM16E, is a crucial player in muscle membrane maintenance and repair processes.
Mutations in the ANO5 gene have been linked to various muscle diseases, including limb-girdle muscular dystrophy and gnathodiaphyseal dysplasia. Understanding the role of ANO5 in muscle physiology is essential for the development of targeted therapies for these disorders.Overall, the ANO5 Polyclonal Antibody provides researchers with a reliable tool for studying the function and regulation of ANO5 in muscle biology, contributing to advancements in the field of muscle disease research.
Product Name:
ANO5 Rabbit Polyclonal Antibody
SKU:
CAB15218
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ANO5 (NP_998764.1).
This gene encodes a member of the anoctamin family of transmembrane proteins. The encoded protein is likely a calcium activated chloride channel. Mutations in this gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
203859
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ANO5 Rabbit pAb (CAB15218) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
