The ANO2 Polyclonal Antibody (CAB3684) is a valuable tool for researchers studying ANO2, a calcium-activated chloride channel involved in various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By specifically binding to the ANO2 protein, this antibody allows for the detection and analysis of ANO2 in different cell types, making it an excellent choice for studies in physiology and neuroscience.ANO2, also known as TMEM16B, plays a crucial role in controlling chloride secretion and neuronal excitability, making it a promising target for research in the fields of gastrointestinal physiology and neurological disorders.
Understanding the function of ANO2 is essential for developing therapies targeting chloride channel dysregulation in diseases such as cystic fibrosis and epilepsy. By utilizing the ANO2 Polyclonal Antibody, researchers can further investigate the role of ANO2 in health and disease, contributing to advancements in biomedical research.
Product Name:
ANO2 Rabbit Polyclonal Antibody
SKU:
CAB3684
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ANO2 (NP_001265526.1).
ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).
Purification Method:
Affinity purification
Gene ID:
57101
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using ANO2 Rabbit pAb (CAB3684) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
