ANXA7 Rabbit Polyclonal Antibody (CAB3733)
- SKU:
- CAB3733
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | ANXA7 Rabbit Polyclonal Antibody |
SKU: | CAB3733 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 237-466 of human ANXA7 (NP_001147.1). |
Sequence: | TYYD AWSL RKAM QGAG TQER VLIE ILCT RTNQ EIRE IVRC YQSE FGRD LEKD IRSD TSGH FERL LVSM CQGN RDEN QSIN HQMA QEDA QRLY QAGE GRLG TDES CFNM ILAT RSFP QLRA TMEA YSRM ANRD LLSS VSRE FSGY VESG LKTI LQCA LNRP AFFA ERLY YAMK GAGT DDST LVRI VVTR SEID LVQI KQMF AQMY QKTL GTMI AGDT SGDY RRLL LAIV GQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | SNX; ANX7; SYNEXIN; ANXA7 |
Positive Sample: | SH-SY5Y,NCI-H460,HepG2,SW480,NIH/3T3,Mouse heart,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | extracellular exosome, nucleus |
Calculated MW: | 53kDa |
Observed MW: | 50kDa |
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
Purification Method: | Affinity purification |
Gene ID: | 310 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |