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Annexin A2 Monoclonal Antibody

SKU:
CAB23279
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
Frequently bought together:

Description

Annexin A2 Monoclonal Antibody (CAB23279)

The Annexin A2 Monoclonal Antibody is a specialized research tool designed for studying Annexin A2, a calcium-dependent phospholipid-binding protein involved in various cellular processes such as membrane trafficking, cell adhesion, and signal transduction. This monoclonal antibody, derived from hybridoma cells, exhibits high specificity and sensitivity towards Annexin A2 in human samples, making it a reliable tool for Western blot, immunofluorescence, and immunohistochemistry applications.Annexin A2 plays a crucial role in cell membrane organization, exocytosis, and intracellular signaling pathways, making it a key player in physiological and pathological processes like cancer metastasis, inflammation, and viral infection.

By targeting Annexin A2, researchers can gain insights into its functional role and potential as a therapeutic target in various diseases. The Annexin A2 Monoclonal Antibody offers a valuable tool for investigating the molecular mechanisms involving Annexin A2, paving the way for innovative research in cell biology, cancer biology, and drug development.

Product Name:Annexin A2 Monoclonal Antibody
Product Code:CAB23279
Reactivity:Human, Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC59617
Reactivity:Human, Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:HeLa, MCF7, LNcap(Low expression control), NIH/3T3
Cellular Location:Melanosome, Secreted, basement membrane, extracellular matrix, extracellular space

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.

Immunogen:Recombinant protein of human Annexin A2.
Sequence:MSTVH EILCK LSLEG DHSTP PSAYG SVKAY TNFDA ERDAL NIETA IKTKG VDEVT IVNIL TNRSN AQRQD IAFAY QRRTK KELAS ALKSA LSGHL ETVIL
Synonyms:P36, ANX2, LIP2, LPC2, CAL1H, LPC2D, ANX2L4, PAP-IV, HEL-S-270
Calculated MW:39kDa
Observed MW:38kDa

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