The Annexin A11 Polyclonal Antibody (CAB7423) is a versatile tool for researchers studying Annexin A11, a calcium-dependent phospholipid-binding protein involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to Annexin A11, researchers can easily detect and analyze the protein in a variety of cell types, making it an excellent choice for studies in cell biology, signal transduction, and membrane trafficking.Annexin A11 is known to play essential roles in membrane dynamics, vesicle trafficking, and cell signaling, making it a key player in processes such as exocytosis and endocytosis.
Its involvement in cellular function makes it a promising target for research into diseases like cancer, neurological disorders, and inflammatory conditions. Understanding the mechanisms behind Annexin A11 activity could lead to the development of novel therapeutic interventions targeting these diseases.Overall, the Annexin A11 Polyclonal Antibody (CAB7423) is a valuable tool for researchers aiming to unravel the complex functions of Annexin A11 and its implications in various cellular processes and diseases.
Product Name:
ANXA11 Rabbit Polyclonal Antibody
SKU:
CAB7423
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 276-505 of human Annexin A11 (NP_001148.1).
This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
311
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat heart , using Annexin A11 Rabbit pAb (CAB7423) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
