The ANKS6 Polyclonal Antibody is a valuable tool for researchers studying ANKS6, a protein involved in cell signaling and gene regulation. This antibody is produced in rabbits and is highly specific for detecting ANKS6 in human samples. Validated for use in Western blot applications, this antibody binds to the ANKS6 protein, allowing for accurate detection and analysis in various cell types.ANKS6 is known to play a role in cellular processes related to development, proliferation, and differentiation. Its involvement in critical signaling pathways makes it a promising target for further research in fields such as oncology and developmental biology.
By gaining a better understanding of ANKS6 function, researchers can uncover potential therapeutic strategies for diseases like cancer and developmental disorders.Overall, the ANKS6 Polyclonal Antibody is an essential tool for scientists aiming to investigate the functions of ANKS6 and its implications in various biological processes. Its high specificity and reliability in detecting ANKS6 make it an ideal choice for studies in cell biology, signal transduction, and disease mechanisms.
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO46594 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO46594 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Required for renal function.
Synonyms:
Ankyrin repeat and SAM domain-containing protein 6 (Ankyrin repeat domain-containing protein 14) (SamCystin) (Sterile α motif domain-containing protein 6) (SAM domain-containing protein 6), ANKS6, ANKRD14 PKDR1 SAMD6
UniProt Protein Function:
ANKS6: Required for renal function. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 9q22.33Disease: Nephronophthisis 16
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein containing multiple ankyrin repeats and a SAM domain. It is thought that this protein may localize to the proximal region of the primary cilium, and may play a role in renal and cardiovascular development. Mutations in this gene have been shown to cause a form of nephronophthisis (NPHP16), a chronic tubulo-interstitial nephritis. [provided by RefSeq, Jul 2015]
