The ANKS1B Polyclonal Antibody (CAB7820) is a valuable tool for researchers studying ANKS1B, a protein involved in various cellular processes such as cell signaling and structure organization. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. By binding to the ANKS1B protein, this antibody allows for the detection and analysis of ANKS1B in different cell types, making it ideal for studies in molecular biology and cell biology research.
ANKS1B is known to play a role in cell growth, proliferation, and differentiation, making it a target of interest in cancer research and developmental biology. Understanding the function of ANKS1B can provide insights into the mechanisms underlying these processes and may lead to the development of novel therapeutic interventions. The ANKS1B Polyclonal Antibody is a valuable tool for further exploration of ANKS1B's role in cellular function and disease pathology.
Product Name:
ANKS1B Rabbit Polyclonal Antibody
SKU:
CAB7820
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 261-510 of human ANKS1B (NP_858056.2).
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
56899
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ANKS1B antibody (CAB7820) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
