The ANKRD54 Polyclonal Antibody (PAC015447) is specifically designed for research involving ANKRD54, a protein involved in regulating gene expression and cell growth. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various research applications, including Western blotting.ANKRD54 is a critical player in cell proliferation and differentiation processes, making it an important target for studies in developmental biology and cancer research.
By binding to the ANKRD54 protein, this antibody allows for precise detection and analysis in different cell types, providing valuable insights into the function of ANKRD54 in various biological processes. Researchers studying gene regulation, cell growth, and cancer biology will find this antibody to be a valuable tool in their studies. Its ability to accurately detect ANKRD54 protein levels makes it an essential component in understanding the role of ANKRD54 in health and disease.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15447(ANKRD54 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse testis tissue, human colon cancer tissue, Primary antibody: PACO15447(ANKRD54 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15447(ANKRD54 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. Interacts (via ankyrin repeat region) with LYN (via SH3-domain) in an activation-independent status of LYN By similarity. Forms a multiprotein complex with LYN and HCLS1 By similarity. Interacts with TSN2, VAV1, DBNL AND LASP1.
Synonyms:
ankyrin repeat domain 54
UniProt Protein Function:
ANKRD54: Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 22q13.1Cellular Component: cytoplasm; midbody; nucleusMolecular Function: protein bindingBiological Process: positive regulation of erythrocyte differentiation
