ANKRD54 Antibody (PACO15447)
- SKU:
- PACO15447
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ANKRD54 Antibody (PACO15447) |
Antibody SKU: | PACO15447 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human ANKRD54 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15447(ANKRD54 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse testis tissue, human colon cancer tissue, Primary antibody: PACO15447(ANKRD54 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15447(ANKRD54 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. Interacts (via ankyrin repeat region) with LYN (via SH3-domain) in an activation-independent status of LYN By similarity. Forms a multiprotein complex with LYN and HCLS1 By similarity. Interacts with TSN2, VAV1, DBNL AND LASP1. |
Synonyms: | ankyrin repeat domain 54 |
UniProt Protein Function: | ANKRD54: Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 22q13.1Cellular Component: cytoplasm; midbody; nucleusMolecular Function: protein bindingBiological Process: positive regulation of erythrocyte differentiation |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q6NXT1 |
NCBI GenInfo Identifier: | 125987708 |
NCBI Gene ID: | 129138 |
NCBI Accession: | Q6NXT1.2 |
UniProt Secondary Accession: | Q6NXT1,Q6ZSB1, Q9UGV1 |
UniProt Related Accession: | Q6NXT1 |
Molecular Weight: | 18,254 Da |
NCBI Full Name: | Ankyrin repeat domain-containing protein 54 |
NCBI Synonym Full Names: | ankyrin repeat domain 54 |
NCBI Official Symbol: | ANKRD54Â Â |
NCBI Official Synonym Symbols: | LIARÂ Â |
NCBI Protein Information: | ankyrin repeat domain-containing protein 54 |
UniProt Protein Name: | Ankyrin repeat domain-containing protein 54 |
UniProt Synonym Protein Names: | Lyn-interacting ankyrin repeat protein |
Protein Family: | Ankyrin repeat domain-containing protein |
UniProt Gene Name: | ANKRD54Â Â |
UniProt Entry Name: | ANR54_HUMAN |