The ANKRD1 Polyclonal Antibody (CAB6192) is a valuable tool for research involving ANKRD1, a key regulator of cellular responses to stress and inflammation. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for a variety of research applications.ANKRD1, also known as cardiac ankyrin repeat protein, is involved in various cellular processes, including gene expression, signal transduction, and protein stability. Its role in regulating cellular responses to stress and inflammation suggests its potential importance in diseases such as cardiovascular disorders, cancer, and neurodegenerative conditions.
Utilizing the ANKRD1 Polyclonal Antibody allows for the detection and analysis of ANKRD1 protein levels in different cell types, enabling researchers to study its functions and mechanisms in various physiological and pathological conditions. This antibody is validated for use in techniques such as Western blot, immunofluorescence, and immunohistochemistry, providing researchers with a reliable tool for investigating ANKRD1 and its implications in human health and disease.
Product Name:
ANKRD1 Rabbit Polyclonal Antibody
SKU:
CAB6192
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human ANKRD1 (NP_055206.2).
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
Purification Method:
Affinity purification
Gene ID:
27063
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Jurkat cells, using ANKRD1 Rabbit pAb (CAB6192) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
