The ANKRD1 Monoclonal Antibody (CAB22096) is a potent tool for research involving ANKRD1, a key protein involved in various cellular processes including cell differentiation and gene expression regulation. This monoclonal antibody, developed and validated by Assay Genie, specifically targets ANKRD1 in human samples and is ideal for use in Western blot, immunofluorescence, and immunoprecipitation applications.ANKRD1, also known as cardiac ankyrin repeat protein, has been implicated in the development and function of cardiac and skeletal muscle, as well as in the regulation of gene transcription in response to various stimuli.
Studies have shown an association between ANKRD1 dysregulation and diseases such as cardiac hypertrophy, muscular dystrophy, and certain cancers. Thus, the ANKRD1 Monoclonal Antibody is an invaluable tool for researchers investigating the role of ANKRD1 in these conditions and exploring potential therapeutic interventions.
Product Name:
ANKRD1 Monoclonal Antibody
SKU:
CAB22096
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human ANKRD1 (NP_055206.2).
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
Purification Method:
Affinity purification
Gene ID:
27063
Clone Number:
ARC55783
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ANKRD1 antibody (CAB22096) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
