The ANKMY2 Polyclonal Antibody (PAC015443) is a valuable tool for researchers studying ANKMY2, a protein involved in various cellular processes. This antibody, derived from rabbits, is highly specific to human ANKMY2 samples and has been validated for use in Western blot applications. By binding to the ANKMY2 protein, this antibody allows for the detection and analysis of ANKMY2 in different cell types, making it ideal for studies in cell biology and molecular biology.ANKMY2 is a protein that plays a crucial role in cellular function, including cell signaling, membrane trafficking, and cytoskeleton organization.
Research on ANKMY2 can provide insights into various biological processes and diseases, such as cancer, neurological disorders, and developmental abnormalities. Understanding the functions and mechanisms of ANKMY2 can lead to the development of targeted therapies and treatments for these conditions.Overall, the ANKMY2 Polyclonal Antibody is a valuable tool for researchers investigating the role of ANKMY2 in cellular processes and diseases. Its high specificity and reliability in Western blot applications make it a valuable asset for studies in cell biology, molecular biology, and related fields.
Antibody Name:
ANKMY2 Antibody (PACO15443)
Antibody SKU:
PACO15443
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human ANKMY2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO15443(ANKMY2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15443(ANKMY2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Background:
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid, protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.
Synonyms:
ankyrin repeat and MYND domain containing 2
UniProt Protein Function:
ANKMY2: May be involved in the trafficking of signaling proteins to the cilia.Chromosomal Location of Human Ortholog: 7p21Cellular Component: ciliumMolecular Function: metal ion binding
