The ANKMY1 Polyclonal Antibody (PAC015442) is a valuable tool for researchers studying ANKMY1, a protein involved in immune function and cell signaling. Produced using rabbits, this antibody demonstrates high reactivity with human samples and has been validated for use in Western blotting applications. By targeting the ANKMY1 protein, this antibody allows for the detection and analysis of ANKMY1 in various cell types, making it an ideal choice for studies in immunology and cancer research.ANKMY1 is a key player in immune regulation and cell signaling pathways, making it a promising target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions.
By understanding the role of ANKMY1 in immune function, researchers can work towards developing new therapies that manipulate immune responses for therapeutic benefit.Overall, the ANKMY1 Polyclonal Antibody offers researchers a reliable tool for studying ANKMY1 and its implications in immune function and disease pathogenesis. Its high specificity and reactivity with human samples make it a valuable asset in the field of immunology research.
Antibody Name:
ANKMY1 Antibody (PACO15442)
Antibody SKU:
PACO15442
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Fusion protein of human ANKMY1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15442(ANKMY1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15442(ANKMY1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
ANKMY1 (ankyrin repeat and MYND domain containing 1), also known as ZMYND13 or TSAL1, is a 941 amino acid, protein that contains seven ANK repeats, three MORN repeats and one MYND-type zinc finger. MORN repeats were first identified in junctophilins, cytoplasmic proteins involved in junctions between the plasma membrane and the ER/SR membrane. The presence of MORN repeats suggests that ANKMY1 may interact with the plasma membrane. The MYND domain consists of a cluster of cysteine and histidine residues, arranged with an invariant spacing to form a potential zinc-binding motif which may be involved in protein-protein interactions.
Synonyms:
ankyrin repeat and MYND domain containing 1
UniProt Protein Function:
ANKMY1: 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 2q37.3Molecular Function: metal ion binding
ankyrin repeat and MYND domain-containing protein 1 isoform 1
NCBI Synonym Full Names:
ankyrin repeat and MYND domain containing 1
NCBI Official Symbol:
ANKMY1Â Â
NCBI Official Synonym Symbols:
ZMYND13Â Â
NCBI Protein Information:
ankyrin repeat and MYND domain-containing protein 1; testis specific ankyrin-like protein 1; testis-specific ankyrin-like protein 1; zinc finger MYND domain-containing protein 13
UniProt Protein Name:
Ankyrin repeat and MYND domain-containing protein 1
UniProt Synonym Protein Names:
Testis-specific ankyrin-like protein 1; Zinc finger MYND domain-containing protein 13