The ANKMY1 Polyclonal Antibody (PAC015441) is a valuable tool for researchers studying ANKMY1, a key protein involved in immune response regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ANKMY1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component of studies in immunology and cancer research.ANKMY1 is a critical factor in immune system balance, playing a crucial role in regulating inflammation and inhibiting allergic responses.
Its importance in immune function modulation positions it as a promising target for exploration in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Uncovering the mechanisms behind ANKMY1 activity is pivotal in the development of treatments that manipulate immune responses for therapeutic benefit in these disease contexts.
Antibody Name:
ANKMY1 Antibody (PACO15441)
Antibody SKU:
PACO15441
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Fusion protein of human ANKMY1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15441(ANKMY1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Background:
ANKMY1 (ankyrin repeat and MYND domain containing 1), also known as ZMYND13 or TSAL1, is a 941 amino acid, protein that contains seven ANK repeats, three MORN repeats and one MYND-type zinc finger. MORN repeats were first identified in junctophilins, cytoplasmic proteins involved in junctions between the plasma membrane and the ER/SR membrane. The presence of MORN repeats suggests that ANKMY1 may interact with the plasma membrane. The MYND domain consists of a cluster of cysteine and histidine residues, arranged with an invariant spacing to form a potential zinc-binding motif which may be involved in protein-protein interactions.
Synonyms:
ankyrin repeat and MYND domain containing 1
UniProt Protein Function:
ANKMY1: 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 2q37.3Molecular Function: metal ion binding
ankyrin repeat and MYND domain-containing protein 1 isoform 1
NCBI Synonym Full Names:
ankyrin repeat and MYND domain containing 1
NCBI Official Symbol:
ANKMY1Â Â
NCBI Official Synonym Symbols:
ZMYND13Â Â
NCBI Protein Information:
ankyrin repeat and MYND domain-containing protein 1; testis specific ankyrin-like protein 1; testis-specific ankyrin-like protein 1; zinc finger MYND domain-containing protein 13
UniProt Protein Name:
Ankyrin repeat and MYND domain-containing protein 1
UniProt Synonym Protein Names:
Testis-specific ankyrin-like protein 1; Zinc finger MYND domain-containing protein 13
