The Ankle2 Polyclonal Antibody (CAB17654) is a vital tool for researchers studying the Ankle2 protein, a key player in cellular processes and signaling pathways related to immune regulation. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an invaluable resource for Western blot applications. By targeting the Ankle2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it perfect for investigations in immunology and cancer research.Ankle2, also known as a crucial regulator of immune responses, plays a significant role in maintaining immune balance by modulating inflammatory processes and suppressing immune reactions.
Its pivotal role in immune function makes it a prime focus for research on diseases such as cancer, autoimmune disorders, and chronic inflammation. Comprehensive understanding of Ankle2's function is imperative for the development of innovative therapies that aim to manipulate immune responses in pathophysiological conditions.In conclusion, the Ankle2 Polyclonal Antibody (CAB17654) serves as an essential tool for researchers delving into the intricate mechanisms of immune regulation and disease pathogenesis. With its high specificity and reliability, this antibody is a valuable asset for advancing our knowledge in immunology and facilitating the development of targeted therapeutic strategies.
Product Name:
ANKLE2 Rabbit Polyclonal Antibody
SKU:
CAB17654
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-450 of human ANKLE2 (NP_055929.1).
This gene encodes a member of the LEM family of inner nuclear membrane proteins. The encoded protein functions as a mitotic regulator through postmitotic formation of the nuclear envelope. Mutations in this gene cause morphology defects in the nuclear envelope and BAF hyperphosphorylation.
Purification Method:
Affinity purification
Gene ID:
23141
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ANKLE2 Rabbit pAb (CAB17654) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
