The ANKK1 Polyclonal Antibody (CAB16178) offered by Assay Genie is specifically designed for research involving the ANKK1 protein, a key player in dopamine neurotransmission and drug addiction. This antibody, raised in rabbits, is highly reactive with human and mouse samples, making it a versatile tool for studying ANKK1 function in various research applications.ANKK1 is a protein kinase that has been linked to various neurological disorders, including substance abuse and psychiatric conditions. The ANKK1 Polyclonal Antibody is validated for use in Western blot and immunohistochemistry applications, allowing for the detection and analysis of ANKK1 expression in different cell types and tissues.
By targeting ANKK1, researchers can gain insights into the molecular mechanisms underlying addictive behaviors and other related disorders. This antibody is essential for studies in neuroscience, pharmacology, and psychiatry, providing a deeper understanding of the role of ANKK1 in both normal brain function and disease pathology.
Product Name:
ANKK1 Rabbit Polyclonal Antibody
SKU:
CAB16178
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ANKK1 (NP_848605.1).
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.
Purification Method:
Affinity purification
Gene ID:
255239
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using ANKK1 Rabbit pAb (CAB16178) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
