The ANKHD1 Polyclonal Antibody (CAB8224) is a valuable tool for researchers studying ANKHD1, a protein involved in cell cycle regulation and gene expression. This antibody, produced in rabbits, is highly specific to human samples and has been rigorously validated for use in Western blot applications. By binding to the ANKHD1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.ANKHD1 is known to play a crucial role in cell proliferation and differentiation, making it a key target for investigations into cancer development and progression.
Additionally, ANKHD1 has been implicated in the regulation of gene transcription, suggesting its potential importance in various cellular functions. Understanding the function of ANKHD1 is essential for uncovering its role in disease processes and may lead to the development of novel therapeutic strategies in the future.
Product Name:
ANKHD1 Rabbit Polyclonal Antibody
SKU:
CAB8224
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1620-1800 of human ANKHD1 (NP_060217.1).
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.
Purification Method:
Affinity purification
Gene ID:
54882
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ANKHD1 antibody (CAB8224) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
