The Anillin Polyclonal Antibody (CAB6524) is a vital tool for researchers studying the protein Anillin, which plays a key role in cell division and cytokinesis. This antibody, produced in rabbit hosts, exhibits high specificity and reactivity towards human samples, making it an excellent choice for Western blot applications.Anillin is a conserved protein that is essential for organizing and contracting the actin cytoskeleton during cell division. Dysfunction in Anillin has been linked to various diseases, including cancers and developmental disorders. By utilizing the Anillin Polyclonal Antibody, researchers can detect and study the expression of Anillin in different cell types, shedding light on its function and potential implications in disease pathology.
With its high sensitivity and specificity, the Anillin Polyclonal Antibody is an invaluable tool for investigations in cell biology, cancer research, and developmental biology. By better understanding the role of Anillin in cellular processes, researchers can pave the way for potential therapeutic interventions targeting Anillin-related pathways in various diseases.
Product Name:
ANLN Rabbit Polyclonal Antibody
SKU:
CAB6524
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 845-1124 of human ANLN (NP_061155.2).
This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
54443
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ANLN antibody (CAB6524) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
