The ANGPTL8 Polyclonal Antibody (CAB18133) is a valuable tool for research on Angiopoietin-like protein 8 (ANGPTL8), a hormone that plays a key role in regulating lipid metabolism and insulin sensitivity. The antibody, produced in rabbits, offers high reactivity with human samples and has been validated for use in Western blot applications.ANGPTL8 is a novel protein that has been shown to control lipid metabolism by regulating triglyceride clearance and promoting fat storage in adipose tissue. It is also involved in the regulation of glucose metabolism and insulin sensitivity, making it a potential target for the treatment of metabolic disorders such as obesity and diabetes.
This antibody binds specifically to ANGPTL8, allowing for the detection and analysis of the protein in various tissue types and cell lines. Its application in research areas such as metabolic disorders, obesity, and diabetes makes it an essential tool for scientists studying the molecular mechanisms underlying these conditions. Understanding the functions of ANGPTL8 could lead to the development of new therapeutic strategies for managing metabolic diseases and improving overall health outcomes.
Product Name:
ANGPTL8 Polyclonal Antibody
SKU:
CAB18133
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-198 of human ANGPTL8 (NP_061157.3).
Predicted to enable hormone activity. Involved in regulation of lipid metabolic process and triglyceride homeostasis. Acts upstream of or within positive regulation of protein processing and regulation of lipoprotein metabolic process. Located in extracellular region.
Purification Method:
Affinity purification
Gene ID:
55908
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ANGPTL8 Rabbit pAb (CAB18133) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
