Angptl8 Antibody (PACO39174)
- SKU:
- PACO39174
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Angptl8 Antibody (PACO39174)
The Angptl8 Polyclonal Antibody (PAC039174) is a valuable tool for researchers studying Angptl8, a protein involved in metabolic regulation and energy homeostasis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.Angptl8, also known as betatrophin, has been linked to the regulation of glucose and lipid metabolism, making it a promising target for research in metabolic disorders such as diabetes and obesity.
By targeting Angptl8, researchers can gain insight into the mechanisms underlying these conditions and potentially identify new therapeutic strategies.This antibody enables the detection and analysis of Angptl8 in different cell types, providing researchers with a powerful tool to advance their studies in metabolic health and disease. With its high reactivity and specificity, the Angptl8 Polyclonal Antibody is an essential resource for researchers exploring the role of Angptl8 in metabolic regulation.
| Antibody Name: | Angptl8 Antibody (PACO39174) |
| Antibody SKU: | PACO39174 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Betatrophin protein (16-198AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Hormone that specifically promotes pancreatic β cell proliferation and β cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic β cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage. |
| Synonyms: | Angiopoietin-like protein 8 (Betatrophin) (Lipasin) (Refeeding-induced fat and liver protein), Angptl8, Gm6484 Rifl |
| UniProt Protein Function: | EG624219: Hormone that specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic beta cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage. In response to food intake. Interacts with ANGPTL3 |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 9|9 A3 Cellular Component: extracellular region Molecular Function:hormone activity Biological Process: cell maturation; cellular lipid metabolic process; fat cell differentiation; glucose metabolic process; negative regulation of lipoprotein lipase activity; regulation of lipid metabolic process; regulation of lipoprotein metabolic process |
| UniProt Code: | Q8R1L8 |
| NCBI GenInfo Identifier: | 124301204 |
| NCBI Gene ID: | 624219 |
| NCBI Accession: | NP_001074409.1 |
| UniProt Related Accession: | Q8R1L8 |
| Molecular Weight: | 22.5kD |
| NCBI Full Name: | angiopoietin-like protein 8 |
| NCBI Synonym Full Names: | angiopoietin-like 8 |
| NCBI Official Symbol: | Angptl8Â Â |
| NCBI Official Synonym Symbols: | Rifl; Gm6484; EG624219Â Â |
| NCBI Protein Information: | angiopoietin-like protein 8 |
| UniProt Protein Name: | Angiopoietin-like protein 8 |
| UniProt Synonym Protein Names: | Betatrophin |
| UniProt Gene Name: | Angptl8Â Â |
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