ANGPTL4 Rabbit Polyclonal Antibody (CAB2011)
- SKU:
- CAB2011
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Description
Product Name: | ANGPTL4 Rabbit Polyclonal Antibody |
SKU: | CAB2011 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-170 of human ANGPTL4 (NP_647475.1). |
Sequence: | GPVQ SKSP RFAS WDEM NVLA HGLL QLGQ GLRE HAER TRSQ LSAL ERRL SACG SACQ GTEG STDL PLAP ESRV DPEV LHSL QTQL KAQN SRIQ QLFH KVAQ QQRH LEKQ HLRI QHLQ SQFG LLDH KHLD HEVA KPAR RKRL PEMA Q |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NL2; ARP4; FIAF; HARP; PGAR; HFARP; TGQTL; UNQ171; pp1158; ANGPTL4 |
Positive Sample: | A-549,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 45kDa |
Observed MW: | 45-50kDa |
This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
Purification Method: | Affinity purification |
Gene ID: | 51129 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |