The ANGPTL3 Rabbit Monoclonal Antibody (CAB5225) is a cutting-edge tool for researchers studying ANGPTL3, a key player in lipid metabolism and cardiovascular health. Developed using rabbit monoclonal technology, this antibody offers high specificity and sensitivity for detecting ANGPTL3 in human samples, making it ideal for use in various experimental settings.ANGPTL3, a member of the angiopoietin-like protein family, is known to regulate lipid levels in the bloodstream by inhibiting lipoprotein lipase activity. Dysregulation of ANGPTL3 has been linked to dyslipidemia, atherosclerosis, and other metabolic disorders, making it an attractive target for drug discovery and clinical research.
By using the ANGPTL3 Rabbit Monoclonal Antibody, researchers can better understand the role of ANGPTL3 in lipid metabolism and cardiovascular disease, paving the way for new therapeutic strategies that target ANGPTL3 for the treatment of various metabolic conditions. This antibody is validated for use in Western blotting, immunohistochemistry, and other research applications, providing reliable and accurate results for your experiments.
Product Name:
ANGPTL3 Rabbit Monoclonal Antibody
SKU:
CAB5225
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ANGPTL3 (Q9Y5C1).
Hep G2,A-375,Mouse lung,Mouse liver,Rat lung,Rat liver
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
54kDa
Observed MW:
63kDa
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
Purification Method:
Affinity purification
Gene ID:
27329
Clone Number:
ARC1214
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ANGPTL3 Rabbit mAb (CAB5225) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
