The Angptl3 Polyclonal Antibody (CAB0689) is a crucial tool for research involving Angptl3, a protein involved in lipid metabolism and cardiovascular health. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in various applications, including Western blotting. By binding to Angptl3, this antibody enables accurate detection and analysis in a range of cell types, making it a valuable resource for studies in cardiovascular disease, metabolism, and lipid biology.Angptl3 is a key player in regulating lipid levels in the blood, making it a promising target for research on conditions like hyperlipidemia, atherosclerosis, and metabolic disorders.
Understanding the function and regulation of Angptl3 is essential for developing effective treatments and interventions to manage these diseases and improve cardiovascular health. By utilizing the Angptl3 Polyclonal Antibody, researchers can gain insights into the mechanisms underlying lipid metabolism and potentially identify novel therapeutic strategies.
Product Name:
ANGPTL3 Rabbit Polyclonal Antibody
SKU:
CAB0689
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 231-460 of human ANGPTL3 (NP_055310.1).
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
Purification Method:
Affinity purification
Gene ID:
27329
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ANGPTL3 antibody (CAB0689) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
