ANGPTL2 Antibody (PACO18560)
- SKU:
- PACO18560
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
ANGPTL2 Antibody (PACO18560)
The ANGPTL2 Polyclonal Antibody (PAC018560) is a valuable tool for research involving ANGPTL2, a protein associated with various physiological functions, including regulation of lipid metabolism and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in applications such as Western blotting and immunohistochemistry. By binding specifically to the ANGPTL2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it well-suited for studies in metabolic disorders, cardiovascular diseases, and immune system dysregulation.
ANGPTL2, also known as Angiopoietin-like 2, is a key mediator in the development of obesity-related complications and chronic inflammatory conditions. Its role in lipid metabolism and inflammatory responses make it a promising target for research aimed at understanding and treating metabolic disorders, cardiovascular diseases, and inflammatory disorders. Investigating the function of ANGPTL2 is crucial for identifying potential therapeutic targets and developing interventions to improve health outcomes in these disease contexts.
| Antibody Name: | ANGPTL2 Antibody (PACO18560) |
| Antibody SKU: | PACO18560 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ANGPTL2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18560(ANGPTL2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse intestinum tenue tissue, Primary antibody: PACO18560(ANGPTL2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18560(ANGPTL2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. |
| Synonyms: | Angiopoietin-like 2 |
| UniProt Protein Function: | ANGPTL2: Induces sprouting in endothelial cells through an autocrine and paracrine action. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 9q33.3 Cellular Component: extracellular space Molecular Function:receptor binding Biological Process: multicellular organismal development |
| NCBI Summary: | Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UKU9 |
| NCBI GenInfo Identifier: | 6912236 |
| NCBI Gene ID: | 23452 |
| NCBI Accession: | NP_036230.1 |
| UniProt Secondary Accession: | Q9UKU9,Q5JT58, Q8NCH7, |
| UniProt Related Accession: | Q9UKU9 |
| Molecular Weight: | |
| NCBI Full Name: | angiopoietin-related protein 2 |
| NCBI Synonym Full Names: | angiopoietin like 2 |
| NCBI Official Symbol: | ANGPTL2Â Â |
| NCBI Official Synonym Symbols: | ARP2; HARPÂ Â |
| NCBI Protein Information: | angiopoietin-related protein 2 |
| UniProt Protein Name: | Angiopoietin-related protein 2 |
| UniProt Synonym Protein Names: | Angiopoietin-like protein 2 |
| Protein Family: | Angiopoietin-related protein |
| UniProt Gene Name: | ANGPTL2Â Â |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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