ANGPT2 Rabbit Monoclonal Antibody (CAB11306)
- SKU:
- CAB11306
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | ANGPT2 Rabbit Monoclonal Antibody |
SKU: | CAB11306 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ANGPT2 (O15123). |
Sequence: | LTFP NSTE EIKA YCDM EAGG GGWT IIQR REDG SVDF QRTW KEYK VGFG NPSG EYWL GNEF VSQL TNQQ RYVL KIHL KDWE GNEA YSLY EHFY LSSE ELNY R |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | ANG2; AGPT2; LMPHM10; ANGPT2 |
Positive Sample: | A-549,HUVEC,Mouse lung,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome.
Purification Method: | Affinity purification |
Gene ID: | 285 |
Clone Number: | ARC0571 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |