The Angpt2 Rabbit Monoclonal Antibody is a high-quality research tool designed for the detection of Angiopoietin 2 (Angpt2), a key player in angiogenesis and vascular permeability. This antibody, produced in rabbits, is highly specific for Angpt2 and has been validated for use in various applications, including Western blot and immunohistochemistry.Angpt2 is a secreted protein that functions as an antagonist of Angiopoietin 1, promoting vascular destabilization and pathological angiogenesis. It is involved in various biological processes, including tumor angiogenesis, inflammation, and tissue repair. The Angpt2 Rabbit Monoclonal Antibody enables precise detection and analysis of Angpt2 protein levels in different cell types and tissues, making it an essential tool for researchers in the fields of vascular biology, cancer research, and inflammation.
By studying the expression and function of Angpt2, researchers can gain valuable insights into the mechanisms underlying angiogenesis and vascular pathology, providing potential targets for therapeutic intervention in diseases such as cancer, cardiovascular disorders, and inflammatory conditions. The Angpt2 Rabbit Monoclonal Antibody is a valuable tool for advancing research in these important areas of study.
Product Name:
ANGPT2 Rabbit Monoclonal Antibody
SKU:
CAB11306
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ANGPT2 (O15123).
This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome.
Purification Method:
Affinity purification
Gene ID:
285
Clone Number:
ARC0571
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ANGPT2 Rabbit mAb (CAB11306) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
